jeudi 21 mai de 14:00 à 15:00
Join us to hear Professor Steve Clifford (Newcastle University, UK) and Dr Don Mabbott (SickKids, Canada) discuss exploiting neurobiology to eradicate cognitive late-effects in childhood brain tumours
About this event
The Brain Tumour Charity warmly welcomes clinical, academic and industry researchers with an interest in the brain tumour field to join our invited speakers.
Survivors of childhood brain tumours are at increased risk of cognitive impairment due to the effects of the tumour and its treatment. We urgently need to understand the mechanisms underlying these late-effects and how to defeat them. In this webinar, our experts will discuss the molecular pathways and neurobiology associated with cognitive late-effects and how this knowledge could be harnessed to develop interventions for prevention and treatment. Join us to hear the latest thinking on this exciting new field, with a chance to ask our experts your questions.
Overview of webinar:
Background to cognitive late-effect molecular pathways
By understanding neurobiology we can influence cognitive late-effects: metformin
Correlation between tumour/host biology and cognitive late-effects
Genetic predictors of cognitive late-effects
Methylphenidate and population-based interventions
Molecular interventions and implications for future treatments
About the speakers
Professor Steve Clifford
Steve is Director of the Newcastle University Centre for Cancer, where he is Professor of Molecular Paediatric Oncology and leads the Paediatric Brain Tumour Research Group at its Wolfson Centre for Childhood Cancer Research.
Steve’s main research interests lie in understanding the biological basis of embryonal brain tumour development (principally medulloblastoma and other embryonal tumours), and translating these findings into improved clinical treatments. He plays leading roles in national and international research networks and clinical trials in medulloblastoma, and directs the UK national reference centre for medulloblastoma molecular diagnostics and pathology review.
Steve is a member of The Brain Tumour Charity’s Scientific Advisory Board and overall lead for the INSTINCT programme.
Dr Don Mabbott
Based in Toronto, Don is a psychologist with Neurosciences and Mental Health Program at The Hospital for Sick Children (SickKids), Program Head / Senior Scientist at SickKids, and a professor in the Department of Psychology at the University of Toronto. He provides clinical neuropsychology services to children with brain tumours and their families.
The overall goal of Don’s research is to reduce the burden of brain tumours and their treatment to improve the quality of life for children. His research aims to understand how perturbed brain development manifests as cognitive impairment in children, particularly in survivors of paediatric brain tumours. Also, to discover how neuroplasticity in the developing brain can be harnessed for neural recovery and cognitive restoration in children with acquired brain injury, including brain tumours. He has recently begun exciting new work to find ways to foster brain repair following radiation injury in children treated for brain tumours, including using physical exercise and drugs that stimulate the growth of new brain cells.
About the organiser
The Brain Tumour Charity is the world's leading brain tumour charity and the largest dedicated funder of research into brain tumours globally.
Committed to saving and improving lives, we're moving further, faster to help every single person affected by a brain tumour. We're set on finding new treatments, offering the highest level of support and driving urgent change. And we're doing it right now. Because we understand that when you, or someone you love, is diagnosed with a brain tumour – a cure really can't wait.
Find out more about our global research funding opportunities here.
If you have any questions, please contact the Research Team on firstname.lastname@example.org or call +44 (0)1252 418190.
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